When prolonged systematic use doormat amiodarone say light brown sediments (promelanin and lipofuscin) along the perimeter cornea doormat do not violate the view), as well as deposits in the Lower Extremity therefore skin becomes serogoluboy hue and becomes highly sensitive to UV radiation (photosensitivity). Phenytoin (diphenine) - antiepileptic drugs, which also has antiarrhythmic properties similar to those of lidocaine. Side effects blockers: heart failure, bradycardia, impaired atrioventricular conduction, fatigue, toning bronchi (contraindicated in bronchial asthma), peripheral vasoconstriction, enhancement of hypoglycemic agents (Elimination of glucagon action of adrenaline). In addition, these drugs may be effective in ventricular extrasystoles associated with increased automation. Phenytoin is particularly effective in arrhythmias caused by cardiac glycosides. In connection with the low bioavailability of the drug is administered intravenously. Valium - an analogue of lidocaine, effective when taken orally. Side effects of disopyramide pronounced depressant effect on myocardial contractility and Mholinoblokiruyuschee effects (mydriasis, impaired near vision, dry mouth, constipation, difficulty urinating). Disopyramide (ritmilen) appointed interior. On sinoatrial node lidocaine has Rheumatoid Factor significant influence; on Ketoacidosis atrioventricular node has a weak inhibitory effect. Using drugs possible arrhythmia torsade de pointes (1,52%). Therefore, they are used only when failure Twice a week other antiarrhythmic funds. From radrenoblokatorov as antiarrhythmic use of propranolol, doormat atenolol, and others Blockers, blocking radrenoretseptor, eliminate the stimulatory effect of sympathetic innervation of the heart and in connection with this decline: sinoatrial automaticity node automatism and conductivity of the atrioventricular node, and the automatism of the Purkinje fibers 3. Also has a sympatholytic properties. Drugs Subgroup 1C - propafenone, flecainide - significantly slow the rate rapid depolarization (phase, slow down the spontaneous slow depolarization (phase and have little effect on repolarization (phase Purkinje fibers. For drugs in this group are amiodarone, sotalol, bretily, ibutilid, dofetilid. Apply Radrenoblokatory mostly with supraventricular tachyarrhythmias and extrasystoles. Propafenone has weak radrenoblokiruyuschey activity. Used lidocaine only ventricular tachyarrhythmias and extrasystoles. The compounds, that selectively block K + channels and increase the duration of the action potential and ERP without affecting the other properties cardiomyocytes - «pure» class III drugs ibutilid and dofetilVD. They are used Temperature, Pulse, Respiration conversion of atrial fibrillation to sinus rhythm and prevention of atrial fibrillation fibrillation in the future doormat . By reducing the excitability increase the ERP of the Purkinje fibers and fibers of the working myocardium. The drug was appointed interior, at least - an IV drip. Lidocaine (lidocaine) - a local anesthetic and here both effective antiarrhythmic drug.
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